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Mohrbooks Literary Agency
Sebastian Ritscher
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English
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THE WINE-DARK SEA WITHIN

Dhun Sethna

The Turbulent History of Blood

The Wine-Dark Sea Within offers a revisionist retelling of the history of Western medicine, centered on the quest to understand the nature of blood.
Physician Dhun Sethna masterfully weaves together a global story, beginning 3,000 years ago in ancient China and India, continuing through ancient Greece and Rome, the Renaissance, and the Age of Enlightenment.

Blood has always been central to our understanding of how the body sustains life. And without a doubt, the most influential description of blood came from Greek physician Galen, who saw health as a function of a person's virtue. In his system, blood ebbed and flowed in the body according to one's behavior. For 1,500 years, the Galenic model of medicine, favored by the Church, reigned supreme. Then, in 1628, an English physician named William Harvey proved that blood does not ebb and flow but rather circulates around the body in a single direction. This discovery is often overlooked, but Sethna argues that it completely changed the course of medicine. Suddenly it was possible to talk about the body in purely secular terms, mechanically, as a system of pumps and pipes. With this insight, Sethna shows that blood circulation paved the way for the foundation of immunology, cardiology, biochemistry, transplant science, and metabolic science. It even influenced the development of thermodynamics and plant respiration.

The Wine-Dark Sea Within is above all a story of great ideas, a story of bitter feuds and historical collaborations, backstabbing, deadly heresies and perseverance, featuring some of the world's most famous thinkers in its cast of characters: Homer, Leonardo, Descartes, Lavoisier. It is a richly detailed and provocative history, told by a stunning new voice in popular science.

Dhun Sethna, MD is currently the Medical Director of Cardiology at the Carilion Clinic, affiliated with Carilion-Virginia Tech Medical School. Previously, he has served as a medical director at Cedars Sinai Medical Center, the Cleveland Clinic, and UCSF Medical School. He lives in Virginia.
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Published 2022-06-07 by Basic Books

Comments

An impressive story; devotees of medical history will have plenty to enjoy.

Simplified Chinese: CITIC (preempt)

[The] account of the circulation of the blood took over two millennia to develop... In The Wine-Dark Sea Within, this process becomes a saga of heroism, villainy and high intellectual adventure, told with great eloquence and verve by Dhun Sethna. Read more...

For something that's inside all of us, it's taken physicians several millennia to understand blood. Dr. Dhun Sethna is a clinical and academic cardiologist. He joins host Krys Boyd to discuss how slowly advancements in our knowledge of blood circulation and the heart progressed, and where these discoveries have taken medicine today. Read more...

[An] intriguing work of scientific history and appreciation of the arduous path to cardiac discovery.

Nature included The Wine-Dark Sea Within in a weekly roundup of best science books earlier this month. The book is praised as "elegant." Read more...

The discovery of how blood circulates in the human body was a seminal scientific event. The Wine-Dark Sea Within presents an engaging and incredibly comprehensive history of this paradigm-shifting breakthrough.

For most of human history, people believed that blood flow was a one-way thing. The discovery that blood flowed two ways - that there was a circulatory system -didn't happen until the mid-1600s. And it took more than a century for that discovery to be formally adopted by most scientific institutions. Abdul goes back in history to help us understand the resistance to science in the present. He interviews Dr. Dhun Sethna, a cardiac anesthesiologist and author of "The Wine Dark Sea Within" about the discovery of the human circulatory system and it's implications for our time. Read more...