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Liepman Literary Agency
Marc Koralnik
Original language
English
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http://www.jayingram.ca/

THE END OF MEMORY : A Natural History of Aging and Alzheimer's

Jay Ingram

The End of Memory: A Natural History of Alzheimer's Disease is noted science writer Jay Ingram's illuminating biography of "the Plague of the 21st Century," a disease that robs its victims of their memory, their ability to think clearly, and ultimately their very lives.
For centuries, those afflicted by Alzheimer's disease have suffered its debilitating effects, with family members watching their loved ones disappear a little more each day until the person they used to know is gone forever. It was in 1901 that German psychologist and neurologist Alois Alzheimer began working with Auguste Deter, a 51-year-old woman suffering from dementia. When several years later upon her death he examined her brain under the microscope, he remarked on two unusual features: dark blobs he called "plaques" and the twisted remnants of neurons, or "tangles". In the century since the disease was first described, there has been a great deal of scientific inquiry into its causes, but little progress in its treatment. Ingram believes we are on the threshold of important new leaps in understanding, and in The End of Memory he explains the fascinating science of plaques and tangles, recounts the imperfect history of our efforts to understand and combat the disease, and introduces us to the passionate researchers who are now working to find a cure. In the spirit of Siddhartha Mukherjee's The Emperor of All Maladies, this is a book for those who want to find out the true story behind an affliction that courses through families and wreaks havoc with the lives of millions. Jay Ingram was the host of Discovery Channel Canada's Daily Planet from the first episode until June 2011. Prior to joining Discovery, Ingram hosted CBC Radio's national science show, Quirks & Quarks. He has received the Sandford Fleming Medal from the Royal Canadian Institute, the Royal Society's McNeil Medal for the Public Awareness of Science and the Michael Smith Award from the Natural Sciences and engineering Research Council. He is a distinguished alumnus of the University of Alberta, has received five honorary doctorates, is a member of the Order of Canada, and is the author of twelve prior books. For more information, please visit www.jayingram.ca.
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Published 2015-09-01 by Harper Collins

Comments

"Jay Ingram offers a cogent and informative history of Alzheimer´s disease and overview of current research ... In clear, accessible, and upbeat prose, Ingram demonstrates his optimism about the possibility of aging with an agile mind, and he is hopeful about finding and effective treatment for sufferers."

TUBITAK

“A personal and professional observation of the impact of [Alzheimer's].”

“With his laidback prose replete with clever analogies and clarifying rhetorical questions, Ingram guides us efficiently through the scientific research.”

Human Science & Technology Press Ltd

American Medical Writers Association's prestigious Walter C. Alvarez Award which honors excellence in communicating health care developments and concepts to the public.

Thomas Dunne Books (Peter Joseph)

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Kokusho Kankokai

"In this riveting tale of Alzheimer's disease, Canadian science writer Ingram (Fatal Flaws) elegantly traces the history of the persistent and devastating ailment and the many medical researchers who have contributed to the public's understanding of it With crackerjack storytelling and fast-paced prose, Ingram examines recent research into Alzheimer's Ingram's first-rate medical writing makes this excellent history a must-read."

“[Ingram's] decades of experience presenting science to a general audience are evident in this book. It is accessible and quickly paced, covering the history of Alzheimer's disease, some notable cases, and several promising avenues of research being explored today.”

Commonwealth Publishing (Complex)