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Mohrbooks Literary Agency
Annelie Geissler |
DOCTORED
Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's
A riveting work of nonfiction from journalist Charles Piller, exposing the series of calculated actions, fabrications and forgeries that may have set back Alzheimer's research by decades.
Nearly seven million Americans live with Alzheimer's disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Piller's Doctored shows that we've quite likely been walking the wrong path to finding a cure all alongled astray by a cabal of self-interested researchers, government accomplices, and corporate greed.
Piller begins with a whistleblower, Vanderbilt professor Matthew Schrag, whose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prize-rumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease. Piller's revelations of Schrag's findings stunned the field and the public.
From there, based on years of investigative reporting, Doctored exposes a vast network of deceit and its players, all the way up to the FDA. Piller uncovers evidence that hundreds of important Alzheimer's research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the field's institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. It is a shocking tale with huge ramifications not only for Alzheimer's disease, but for scientific research, funding, and oversight at large.
Charles Piller is an Investigative Correspondent for Science, one of the world's preeminent scholarly journals, and has received more than 35 honors from a wide variety of awarding bodies. His work has been nominated for the Pulitzer Prize nine times by STAT, the Los Angeles Times, and The Sacramento Bee. He is the author of two previous books: The Fail-Safe Society: Community Defiance and the End of American Technological Optimism (Basic Books) and Gene Wars: Military Control Over the New Genetic Technologies (with Keith R. Yamamoto; Beech Tree Books).
Piller begins with a whistleblower, Vanderbilt professor Matthew Schrag, whose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prize-rumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease. Piller's revelations of Schrag's findings stunned the field and the public.
From there, based on years of investigative reporting, Doctored exposes a vast network of deceit and its players, all the way up to the FDA. Piller uncovers evidence that hundreds of important Alzheimer's research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the field's institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. It is a shocking tale with huge ramifications not only for Alzheimer's disease, but for scientific research, funding, and oversight at large.
Charles Piller is an Investigative Correspondent for Science, one of the world's preeminent scholarly journals, and has received more than 35 honors from a wide variety of awarding bodies. His work has been nominated for the Pulitzer Prize nine times by STAT, the Los Angeles Times, and The Sacramento Bee. He is the author of two previous books: The Fail-Safe Society: Community Defiance and the End of American Technological Optimism (Basic Books) and Gene Wars: Military Control Over the New Genetic Technologies (with Keith R. Yamamoto; Beech Tree Books).
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